To celebrate the Apollo moon landing's 50th anniversary, Professor Brian Cox and Dara O Briain travel to where the historic Apollo 11 mission began – Cape Canaveral in Florida. They hear first hand from astronaut general Charlie Duke what it was like to guide Neil Armstrong and Buzz Aldrin to the surface of the Moon in the Lunar Lander and how he followed in their footsteps three years later. They also look at the most exciting new developments and, with privileged access, they broadcast from the top of launch tower that is being prepared for crewed missions and from the assembly line of a spacecraft factory. They are joined by astrophysicist and medic Dr Kevin Fong and mathematician Dr Hannah Fry, who explore the latest developments in human space flight - from cutting-edge spacewalk technology to a future Mars buggy.